The use of light for the treatment of human diseases is a very old way, as early as thousands of years ago in China and other countries when the use of sunlight to treat diseases. LED as a new light source, with its biological effect is gradually recognized, is gradually being used and play an active role in medicine, this article will explain in detail and describe the application of LED in medicine in the skin.
Optical parameters that affect the biological effects of LED
The biological effects of LED depend on different optical parameters, including different wavelength, flow rate, intensity, irradiation time, continuous wave or pulse wave, and the number of treatment, treatment interval and so on. Different wavelengths can reach different positions in the skin tissue (Figure 1). Generally speaking, the longer the wavelength, the stronger penetration ability, the penetration of the skin tissue in 400nm distance of not more than 1mm, 514nm penetration distance of about 0.5mm~2mm, 630nm penetration distance of about 1mm~6mm. At the same time, different wavelengths of light can be absorbed by different color groups in the tissue. Red in the clinic (630nm~700nm) was used for the treatment of skin deep structure, such as sebaceous glands; for the treatment of skin lesions in the skin of the blue light in the photodynamic therapy; if you want to reach the dermal layer of the skin is in need of longer wavelengths such as 660nm wavelength to the reticular layer of dermis in the dermis of skin fiber cells play a role, and this is one of the LED light source for the principle of photorejuvenation.
Two, the application of LED in Department of Dermatology
1 photorejuvenation (photo rejuvenation)
Photorejuvenation technology is defined as the use of continuous intense pulsed light at low energy density for the non stripping of the tender skin treatment. Since its inception in 2000, just a few years, the rapid popularization of photorejuvenation technology, has been widely used in various large and medium-sized city, has become one of the main means to improve skin photoaging, this technique can significantly improve the skin wrinkles, rough texture, irregular pigmentation and large pores and other phenomena, has attracted many technology professionals beauty and demands recognition. The characteristic histological change of skin photoaging is the disorder of elastic fibers and collagen fibers in the dermis.
The study found that the visible light to near infrared LED light to penetrate the skin epidermis into the dermis layer of the skin, through the thermal and photochemical effect, the elastic fibers and collagen fibers regeneration and re arranged to reduce skin wrinkles, increase the elasticity of the effect.
2 prevention or treatment of hyperpigmentation after inflammation
Skin pigmentation after inflammation is common and difficult to avoid in the physical and chemical beauty of the skin, especially in Asian populations. For example in the clinic for degree of skin pigmentation decreased after laser treatment, generally avoid excessive ultraviolet season, ask the patient to avoid the sun, sunscreen, but post inflammatory pigmentation is difficult to completely avoid. In recent years, studies have found that 660nm LED light can prevent and even treat the skin pigmentation after the inflammation, which will be a new research focus in the skin beauty industry.
3 to promote wound healing
It can be seen that near infrared band LED light can promote the growth of epithelial cells and promote wound healing. At the same time, it also has a good therapeutic effect on the healing of chronic ulcer of lower limbs in patients with diabetes mellitus.
4 reduce inflammation
A series of studies have shown that LED has anti-inflammatory effect. It was found that the LED light of 635nm can inhibit the release of inflammatory mediators, E2 (PGE2), in gingival fibroblasts, which can reduce the inflammatory reaction of gingiva. In order to reduce the discomfort of skin erythema, swelling and pain caused by dye laser, the LED laser irradiation can be used in the treatment of skin photoaging. Pre irradiation with LED light source can reduce the side effects of radiotherapy in patients with breast cancer before radiotherapy.
5 scar prevention
Keloid is a kind of skin disease which can affect the beauty and the difficulty of treatment. Patients often have scar constitution. Start small and hard red papules, slow increase in clinical, have round, oval or irregular scar, high leather, a crab like outstretched, skin smooth, shiny, accompanied by pain, itching and discomfort. The clinical treatment is difficult and the curative effect is not ideal. Studies have found that LED can significantly improve the patient's pain, itching and other discomfort, so that the flat scar, while the advantages of non-invasive.
6 other effects
In addition, LED can also be used as a non UV phototherapy equipment for photodynamic therapy, treatment of hair loss, reduce skin damage after UV irradiation, etc..
In conclusion, as a new light source, LED has been gradually applied to the skin in medicine, with the mechanism of the biological effects of LED for continuous innovation and medicine on LED lamps, the application of LED in skin medicine will have limitless prospects. At the same time, LED has high safety and can be used as a family medical equipment.
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